788 research outputs found

    Resource Allocation in SDN/NFV-Enabled Core Networks

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    For next generation core networks, it is anticipated to integrate communication, storage and computing resources into one unified, programmable and flexible infrastructure. Software-defined networking (SDN) and network function virtualization (NFV) become two enablers. SDN decouples the network control and forwarding functions, which facilitates network management and enables network programmability. NFV allows the network functions to be virtualized and placed on high capacity servers located anywhere in the network, not only on dedicated devices in current networks. Driven by SDN and NFV platforms, the future network architecture is expected to feature centralized network management, virtualized function chaining, reduced capital and operational costs, and enhanced service quality. The combination of SDN and NFV provides a potential technical route to promote the future communication networks. It is imperative to efficiently manage, allocate and optimize the heterogeneous resources, including computing, storage, and communication resources, to the customized services to achieve better quality-of-service (QoS) provisioning. This thesis makes some in-depth researches on efficient resource allocation for SDN/NFV-enabled core networks in multiple aspects and dimensionality. Typically, the resource allocation task is implemented in three aspects. Given the traffic metrics, QoS requirements, and resource constraints of the substrate network, we first need to compose a virtual network function (VNF) chain to form a virtual network (VN) topology. Then, virtual resources allocated to each VNF or virtual link need to be optimized in order to minimize the provisioning cost while satisfying the QoS requirements. Next, we need to embed the virtual network (i.e., VNF chain) onto the substrate network, in which we need to assign the physical resources in an economical way to meet the resource demands of VNFs and links. This involves determining the locations of NFV nodes to host the VNFs and the routing from source to destination. Finally, we need to schedule the VNFs for multiple services to minimize the service completion time and maximize the network performance. In this thesis, we study resource allocation in SDN/NFV-enabled core networks from the aforementioned three aspects. First, we jointly study how to design the topology of a VN and embed the resultant VN onto a substrate network with the objective of minimizing the embedding cost while satisfying the QoS requirements. In VN topology design, optimizing the resource requirement for each virtual node and link is necessary. Without topology optimization, the resources assigned to the virtual network may be insufficient or redundant, leading to degraded service quality or increased embedding cost. The joint problem is formulated as a Mixed Integer Nonlinear Programming (MINLP), where queueing theory is utilized as the methodology to analyze the network delay and help to define the optimal set of physical resource requirements at network elements. Two algorithms are proposed to obtain the optimal/near-optimal solutions of the MINLP model. Second, we address the multi-SFC embedding problem by a game theoretical approach, considering the heterogeneity of NFV nodes, the effect of processing-resource sharing among various VNFs, and the capacity constraints of NFV nodes. In the proposed resource constrained multi-SFC embedding game (RC-MSEG), each SFC is treated as a player whose objective is to minimize the overall latency experienced by the supported service flow, while satisfying the capacity constraints of all its NFV nodes. Due to processing-resource sharing, additional delay is incurred and integrated into the overall latency for each SFC. The capacity constraints of NFV nodes are considered by adding a penalty term into the cost function of each player, and are guaranteed by a prioritized admission control mechanism. We first prove that the proposed game RC-MSEG is an exact potential game admitting at least one pure Nash Equilibrium (NE) and has the finite improvement property (FIP). Then, we design two iterative algorithms, namely, the best response (BR) algorithm with fast convergence and the spatial adaptive play (SAP) algorithm with great potential to obtain the best NE of the proposed game. Third, the VNF scheduling problem is investigated to minimize the makespan (i.e., overall completion time) of all services, while satisfying their different end-to-end (E2E) delay requirements. The problem is formulated as a mixed integer linear program (MILP) which is NP-hard with exponentially increasing computational complexity as the network size expands. To solve the MILP with high efficiency and accuracy, the original problem is reformulated as a Markov decision process (MDP) problem with variable action set. Then, a reinforcement learning (RL) algorithm is developed to learn the best scheduling policy by continuously interacting with the network environment. The proposed learning algorithm determines the variable action set at each decision-making state and accommodates different execution time of the actions. The reward function in the proposed algorithm is carefully designed to realize delay-aware VNF scheduling. To sum up, it is of great importance to integrate SDN and NFV in the same network to accelerate the evolution toward software-enabled network services. We have studied VN topology design, multi-VNF chain embedding, and delay-aware VNF scheduling to achieve efficient resource allocation in different dimensions. The proposed approaches pave the way for exploiting network slicing to improve resource utilization and facilitate QoS-guaranteed service provisioning in SDN/NFV-enabled networks

    First-Principles Investigation of Anistropic Hole Mobilities in Organic Semiconductors

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    We report a simple first-principles-based simulation model (combining quantum mechanics with Marcus−Hush theory) that provides the quantitative structural relationships between angular resolution anisotropic hole mobility and molecular structures and packing. We validate that this model correctly predicts the anisotropic hole mobilities of ruberene, pentacene, tetracene, 5,11-dichlorotetracene (DCT), and hexathiapentacene (HTP), leading to results in good agreement with experiment

    COMSOL Simulation of MEMS Piezoelectrically Actuated Micropump

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    In this poster, the design and COMSOL simulation of a piezoelectric micropump with dome-shaped diaphragms and diffuser-nozzle fluid rectifiers is reported. The micropump uses piezoelectric ZnO film (less than 10μm thick) to actuate the vibration of a parylene dome diaphragm, so that microfluid can be pumped in and out of the chamber. The device is to be fabricated on silicon substrate with an IC-compatible process. Piezoelectric ZnO film is sputter-deposited on a parylene dome diaphragm with its C-axis oriented perpendicular to the dome surface. The micropump utilizes two symmetric dome diaphragms for improved pumping rate. Diffuser-nozzle elements are integrated with piezoelectrically actuated dome diaphragms to form a multi-chip micropump. Due to the MEMS (Microelectromechanical Systems) technology used, the proposed micropump has very small size (10×10×1.6mm3) and consumes extremely low power. It also shows negligible leakage up to 700 Pa static differential pressure. The function of the proposed micropump is verified with COMSOL simulation

    Biases and improvements of the boreal winter–spring equatorial undercurrent in the Indian Ocean in the CMIP5 and CMIP6 models

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    We assessed the performance of state-of-the-art coupled models in reproducing the equatorial undercurrent (EUC) in the Indian Ocean based on the outputs of the Coupled Model Intercomparison Project Phase 6 (CMIP6) models and compared with the Phase 5 (CMIP5) models. Our results showed that the CMIP6 models reproduced the boreal winter–spring Indian Ocean EUC more realistically than the CMIP5 models, although both generations of models underestimated the strength of the Indian Ocean EUC compared with the observations. This underestimation of the Indian Ocean EUC can be attributed to the excessively strong and westward-extended cold tongue in the equatorial Pacific. In the CMIP models, a stronger winter-mean cold tongue favors a stronger zonal sea surface temperature gradient, which forces a strong easterly wind bias over the equatorial western Pacific. This, in turn, contributes to an acceleration of the Walker circulation. This enhanced Walker circulation over the Indo-Pacific Ocean directly causes a lower level westerly wind bias over the equatorial Indian Ocean and drives a shallow west–deep east thermocline tilt bias, ultimately leading to an excessively weak EUC in the Indian Ocean via wind-induced thermocline processes. Compared with the CMIP5 models, the overall improvement in the strength of the winter–spring Indian Ocean EUC in the CMIP6 models can be traced back to the improvement in the degree of the strong and westward-extended cold tongue bias. Our results suggest that efforts should be made to reduce the bias in the mean-state equatorial Pacific sea surface temperature to further improve the simulation and projection of the atmospheric and oceanic circulations in the Indian Ocean

    Radiation recall pneumonitis induced by chemotherapy after thoracic radiotherapy for lung cancer

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    <p>Abstract</p> <p>Background</p> <p>Radiation recall pneumonitis (RRP) describes a rare reaction in previously irradiated area of pulmonary tissue after application of triggering agents. RRP remains loosely characterized and poorly understood since it has so far only been depicted in 8 cases in the literature. The objective of the study is to disclose the general characteristics of RRP induced by chemotherapy after thoracic irradiation for lung cancer, and to draw attention to the potential toxicity even after a long time interval from the previous irradiation.</p> <p>Methods</p> <p>Medical records were reviewed. RRP induced by chemotherapy was diagnosed by the history of chemotherapy after radiotherapy, clinical presentation and radiographic abnormalities including ground-glass opacity, attenuation, or consolidation changes within the radiation field, plus that radiographic examination of the thorax before showed no radiation pneumonitis. RRP was graded according to Common Terminology Criteria for Adverse Events version 3.0. The characteristics of the 12 RRP cases were analyzed.</p> <p>Results</p> <p>Twelve patients were diagnosed of RRP, of who 8 received taxanes. The median time interval between end of radiotherapy and RRP, between end of radiotherapy and beginning of chemotherapy, and between beginning of chemotherapy and RRP was 95 days, 42 days and 47 days, respectively. Marked symptomatic and radiographic improvement was observed in the 12 patients after withdrawal of chemotherapy and application of systemic corticosteroids. Seven patients were rechallenged with chemotherapy, of whom four with the same kind of agents, and showed no recurrence with steroid cover.</p> <p>Conclusions</p> <p>Doctors should pay attention to RRP even after a long time from the previous radiotherapy or after several cycles of consolidation chemotherapy. Taxanes are likely to be associated with radiation recall more frequently. Withdrawal of causative agent and application of steroids are the treatment of choice. Patients may be rechallenged safely with steroid cover and careful observation, which needs to be validated.</p
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